BEYOND GLYCAN BARRIERS: NON-COGNATE LIGANDS AND PROTEIN MIMICRY APPROACHES TO ELICIT BROADLY NEUTRALIZING ANTIBODIES FOR HIV-1

Beyond glycan barriers: non-cognate ligands and protein mimicry approaches to elicit broadly neutralizing antibodies for HIV-1

Abstract Human immunodeficiency virus type 1 (HIV-1) vaccine immunogens capable of inducing broadly neutralizing antibodies (bNAbs) remain obscure.HIV-1 evades immune responses through Pin Switch enormous diversity and hides its conserved vulnerable epitopes on the envelope glycoprotein (Env) by displaying an extensive immunodominant glycan shield.

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Impulsivity, Sensation Seeking, and Risk-Taking Behaviors among HIV-Positive and HIV-Negative Heroin Dependent Persons

Objective.The aim of this study was to compare impulsivity and risky decision making among HIV-positive and negative heroin dependent persons.Methods.We compared different dimensions of impulsivity and risky decision making in two groups of 60 HIV-positive and 60 HIV-negative male heroin dependent persons.Each group was comprised of equal numbers o

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